JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES)

• Articles • Previous Articles     Next Articles

Long-term effect of massive allograft bones implantation on defects: a more than 20 years observation

ZHANG Shuai1，LI Jian-min1，FENG Rong-jie2，LI Zhen-feng1， LIU Wen-guang1，LIU Liang3，LI Dong1，YANG Jing-yan1   

  1. Department of Orthopaedics， 1. Qilu Hospital of Shandong University， Jinan 250012, China; 2. Shandong Provincial Hospital Affiliated to Shandong University， Jinan 250021, China; 3. Shandong Police Hospital, Jinan 250002, China
  • Received:2007-09-15 Revised:1900-01-01 Online:2008-03-16 Published:2008-03-16
  • Contact: LI Jian-min

PDF (PC)

631

Abstract: To explore the longterm effects and complications of large segment allografts in the treatment for bone tumors． MethodsA retrospective analysis of 32 consecutive cases, 34 to 72 years old, of large segment allograft implantations following resection of bone tumor was conducted. 25 cases had aggressive giantcell tumors of bones, 2 had chondrosarcoma and 5 had other bone tumors. The mean length of the grafts was 18.5cm (ranged 1030cm). 15 cases received fixation with common intramedullary nailing, 13 with plates, and 4 with screws. ResultsFollowed up from 21 to 28 years (average 24.5 years), 30 cases had union and 2 cases did not. Major complications happened in 2 cases, infection in 1 case, fracture in 6 cases, bone absorption in 3 cases, and arthrokleisis in 7 cases. Based on the Mankin system, 4 cases had excellent results, 21 cases had good results, and 1 case had a fair result. The satisfactory rate was 81.3%. ConclusionAllograft bones implantation is reliable in the long term for repairing the bone deflected in the course of limb salvage following resections of bone tumors. Osteoarthritis is the main complication that affects the longterm quality of life.

Key words: Bone transplatation, Allogeneic, Treatment outcome, Long-term

CLC Number: 

  • R68
[1] LU Shengxun, XING Yachuang, LUO Junhui, LIU Jie, HE Houle, WANG Zhiqiang, ZHANG Na. Diabetic patients arterial grafts in coronary artery bypass grafting: current research status [J]. Journal of Shandong University (Health Sciences), 2025, 63(5): 33-39.
[2] SHAO Changxiu, HE Qingqing, ZHANG Xiaoxuan, ZHOU Peng, LI Xiaolei, YUE Tao, XU Jing, LI Chenyu, GUO Haonan, ZHUANG Dayong. Long-term efficacy of total parathyroidectomy with trace parathyroid tissue autotransplantation in the treatment of 109 cases of renal secondary hyperparathyroidism [J]. Journal of Shandong University (Health Sciences), 2023, 61(4): 42-48.
[3] PENG Chao, ZHOU Yingfang. Progress on the medical treatment of adenomyosis [J]. Journal of Shandong University (Health Sciences), 2022, 60(7): 20-25.
[4] LIANG Ziting, XU Changjuan, ZENG Rong, ZHANG Jintao, ZENG Qingshi, DONG Liang. Clinical characteristics of bronchiolitis obliterans syndrome after allogeneichematopoietic stem cell transplantation in 9 children [J]. Journal of Shandong University (Health Sciences), 2022, 60(12): 58-62.
[5] ZHU Dawei, YU Baorong. Demand for long-term care—based on Monte Carlo simulation [J]. Journal of Shandong University (Health Sciences), 2019, 57(8): 82-88.
[6] JIANG Tian, YU Baorong, ZHU Dawei. Funding sources and funding criteria of elderly long-term care insurance [J]. Journal of Shandong University (Health Sciences), 2019, 57(8): 95-102.
[7] SUN Feifei, FANG Xiaosheng, JIANG Yujie, SUI Xiaohui, LIU Xin, WANG Xianghua, LI Ying, ZHANG Lingyan, XU Hongzhi, WANG Xin. Graft-versus-host disease secondary to allogeneic hematopoietic stem cell transplantation in 57 patients with acute lymphoblastic leukemia [J]. Journal of Shandong University (Health Sciences), 2019, 57(7): 61-66.
[8] LENG Jinhua, SHI Jinghua. Long-term management strategy of endometriosis [J]. Journal of Shandong University (Health Sciences), 2019, 57(6): 1-5.
[9] TIAN Ning, CHEN Yi, HAN Wenli, ZHANG Xiaofeng. A clinical analysis of pelvic arterial embolization for postpartum hemorrhage [J]. Journal of Shandong University (Health Sciences), 2019, 57(12): 86-91.
[10] FENG Zhiyu, YANG Yanliang, GUO Rui, XU Huihui, ZHANG Jian, GUO Kai, WANG Guangzhen, WANG Hui. Diagnosis and surgical treatment of pulmonary artery sling complicated with tracheal stenosis [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(8): 48-51.
[11] GAO Jianbu, YANG Shouzhong, LI Yudong, QIAO Chong, ZHANG Songyu. Trend survey of inpatient use of drugs for acute myocardial infarction during 10 years in a hospital of Nanyang City [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(5): 66-69.
[12] WANG Runmei, YANG Qiuhong, ZHANG Fang, MA Yuyan. Long-term prognosis of women preeclampsia and risks of incidence in their female offspring [J]. Journal of Shandong University (Health Sciences), 2017, 55(12): 31-35.
[13] FENG Zhiyu, GUO Rui, YANG Yanliang, LI Haiming, DONG Mingliang, XU Huihui, LIU Yimin, GUO Kai, WANG Guangzhen, WANG Hui. Initial palliative repair of pulmonary atresia with ventricular septal defect by rehabilitating right ventricle to pulmonary artery connection [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2015, 53(11): 41-45.
[14] LU Qian-qian, LIANG Jing, LIU Xiao-lin, LI Yan. Inhibition of allogeneic CD3AK cells on human renal cell carcinoma xenografts in SCID mice [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2014, 52(2): 33-37.
[15] JIANG Da-qing, GU Tian-xiang, FANG Qin, ZHANG Yu-hai. Analysis of independent factor influencing the long-term mortality of
elderly patients(age more than 70 years old) undergoing
coronary artery bypass grajb surgery [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2012, 50(2): 123-.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Copyright 2018 © Editorial office of Journal of Shandong University (Health Sciences)
Supported by Beijing Magtech Co.Ltd