JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2009, Vol. 47 ›› Issue (12): 6-8.

• Articles • Previous Articles     Next Articles

Determination of serum visfatin level in type 2 diabetes mellitus complicated with coronary heart disease and its influencing factors

CHANG Lirong 1 ,  ZHOU Guixia 2 ,  BI Xijuan 3   

  1. 1.Department of Clinical Medicine; 2. Department of Physical Testing, Attached Hospital;
    3. Jitang College,  North China Coal Medical University, Tangshan 063000, Hebei, China
  • Received:2009-06-19 Online:2009-12-16 Published:2009-12-16

PDF (PC)

406

Abstract:

To investigate the level of plasma visfatin and its influencing factors in patients with type 2 diabetes mellitus(T2DM) complicated with coronary heart disease (CHD). MethodsThe levels of visfatin and fasting insulin (FINS) in patient with T2DM, T2DM complicated with CHD and normal controls were measured by ELISA, and fasting plasma glucose (FPG) was measured by an automatic biochemistry analyzer. Body height and weight were measured to calculate body mass index(BMI) and waist to hip ratio(WHR). ResultsThe levels of serum visfatin in the two T2DM groups were higher than that in the normal control group (P<0.01). The level of visfatin in the group of T2DM complicated with CHD was higher than that in the group of T2 DM (P<0.01). Visfatin was positively correlated with HomaIR and WHR (P<0.01). The visfatin level was positively correlated with the numbers of involved coronary arteries(P<0.01). ConclusionsVisfatin plays an important role in the occurrence and development of T2DM and T2DM complicated with CHD. 

Key words: Visfatin, Type 2 diabetes mellitus, Coronary heart disease, Insulin resistance

CLC Number: 

  • R587.1
[1] ZHANG Yuan, LI Yang-Min, FENG Rue-Qiu, CHANG Cai-Yun, PAN Hua-Wei, WANG Shu-Mei. Relationship among serum adiponectin level, obesity and insulin resistance [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2209, 47(6): 124-.
[2] MENG Xiaomei, HAO Yaping, WANG Liang, YU Xiao, TANG Yuxiao. Correlation between the levels of serum Isthmin1, Gremlin2 and retinopathy in type 2 diabetic patients [J]. Journal of Shandong University (Health Sciences), 2025, 63(9): 102-107.
[3] SHEN Lujia, LU Tianwei, GONG Weiming, ZHAO Yansong, WANG Shukang, YUAN Zhongshang. Application of metabolomic risk score in predicting cardiovascular outcomes in patients with type 2 diabetes mellitus [J]. Journal of Shandong University (Health Sciences), 2025, 63(8): 69-78.
[4] CHEN Yingying, WANG Lu, HU Xifeng, ZHU Gaopei, XUE Fuzhong. A Bayesian network-based risk prediction study of stroke in patients with type 2 diabetes mellitus [J]. Journal of Shandong University (Health Sciences), 2025, 63(8): 94-102.
[5] CHEN Xujun, SHEN Lin, CHEN Jun, YU Tao, CAO Guangqing, XIAO Fei. Anatomic complete revascularization is a new strategy of surgical treatment for coronary heart disease [J]. Journal of Shandong University (Health Sciences), 2025, 63(5): 12-17.
[6] GUO Ke, CHEN Xujun, ZHENG Baoshi, HUANG Keli, WANG Xiaowu, CHEN Jingwei, LIN Yu, LUO Junhui, WANG Haichen, WANG Zhendong, LIAO Chengquan, LI Youjin, CHEN Wensheng. Multi-center mid-term clinical outcomes in coronary patients undergoing total arterial bypass surgery with anatomic complete revascularization in China [J]. Journal of Shandong University (Health Sciences), 2025, 63(5): 18-25.
[7] YANG Huimin, GONG Wanli, HOU Yaqi, WU Jing, WANG Yang, HE Peifeng, YU Qi. Causal association between 20 amino acids and coronary heart disease: a Mendelian randomization study [J]. Journal of Shandong University (Health Sciences), 2025, 63(12): 6-16.
[8] LIU Lin, WANG Xiaonan, YANG Yaxi, WANG Jiangteng, LI Xu, ZHOU Xinli, GUAN Qingbo, ZHANG Xu. Correlation of triglycride-glucose index and atherosclerotic stenosis in intracranial arteries [J]. Journal of Shandong University (Health Sciences), 2024, 62(8): 93-100.
[9] LI Jinquan, GAO Meifang, YAN Fei, DONG Ming. Frequency and risk factors of muscle cramp in 136 cases of type 2 diabetes mellitus [J]. Journal of Shandong University (Health Sciences), 2023, 61(5): 20-24.
[10] HAN Chuang, CHENG Chuanlong, LI Chunyu, LIU Ying, FANG Qidi, CUI Feng, YANG Shuxia, HAN Peng, LI Xiujun. Short-term effects of diurnal temperature range on hospital admissions for coronary heart disease in Zibo City [J]. Journal of Shandong University (Health Sciences), 2023, 61(4): 111-118.
[11] HAN Mei, MENG Weijing, TAO Zikun, YANG Xi, XU Yaqi, MU Huaxia, BU Weixiao, WANG Suzhen, SHI Fuyan. Causal mediation analysis with multiple-mediator of hypertension and depression between type 2 diabetes mellitus and cognitive function based on G-computation [J]. Journal of Shandong University (Health Sciences), 2023, 61(10): 101-108.
[12] ZHAO Meiru, ZHU Di, LIU Lin, GUAN Qingbo, ZHANG Xu. Association of 4 simple insulin resistance indicators with the risk of hyperuricemia in 698 patients with type 2 diabetes mellitus [J]. Journal of Shandong University (Health Sciences), 2022, 60(12): 44-51.
[13] XIE Jiaying, QI Jia, SONG Ming, LI Yulin, WANG Di, JIA Xu, ZHANG Wei, ZHONG Ming, SHANG Yuanyuan. Association between serum β-sheet level and coronary heart disease [J]. Journal of Shandong University (Health Sciences), 2022, 60(1): 21-26.
[14] LYU Li, JIANG Lu, CHEN Shihong, ZHUANG Xianghua, SONG Yuwen, WANG Dianhui, AN Wenjuan, LI Qian, PAN Zhe. Related factors of osteoporosis in 210 postmenopausal women with type 2 diabetes mellitus [J]. Journal of Shandong University (Health Sciences), 2021, 59(7): 19-25.
[15] ZHENG Fengjie, SONG Yuwen, SUN Aili, PAN Zhe, WANG Dianhui, LOU Nengjun, LYU Li, ZHUANG Xianghua, CHEN Shihong. Correlation between diabetic peripheral neuropathy and sarcopenia [J]. Journal of Shandong University (Health Sciences), 2021, 59(6): 38-44.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Copyright 2018 © Editorial office of Journal of Shandong University (Health Sciences)
Supported by Beijing Magtech Co.Ltd