Journal of Shandong University (Health Sciences) ›› 2023, Vol. 61 ›› Issue (5): 59-67.doi: 10.6040/j.issn.1671-7554.0.2022.0936

• 临床医学 • Previous Articles    

Functional outcomes of 376 patients with supratentorial spontaneous intracerebral hemorrhage based on radiomic parameters

LIU Yan1, LENG Shanshan2, XIA Xiaona1, DONG Hao3, HUANG Chencui3, MENG Xiangshui1   

  1. 1. Department of Radiology, Qilu Hospital(Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao 266035, Shandong, China;
    2. Department of Radiology, Qingdao Municipal Hospital, Qingdao 266011, Shandong, China;
    3. Department of Research Collaboration, R&
    D Center, Beijing Deepwise &
    League of PHD Technology Co., Ltd., Beijing 100080, China
  • Published:2023-05-15

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Abstract: Objective To investigate the value of a radiomic nomogram model based on initial CT scan to predict the 90-day functional outcomes of supratentorial spontaneous intracerebral hemorrhage(sICH). Methods Clinical data of 376 patients with supratentorial sICH were retrospectively analyzed. According to the 90-day modified Rankin Scale(mRS), the patients were divided into poor outcome group(n=121, mRS score 4-6)and good outcome group(n=255, mRS score 0-3). Radiomic features were extracted from the initial CT scan, radiomic score(Rad-score)was calculated and a radiomic model was constructed. The clinical risk factors of poor outcome were selected to construct a clinical model, and then combined with Rad-score to construct a nomogram model. The diagnostic values of the three models were compared. Results Altogether 20 features were selected to establish the radiomic model. The clinical model was composed of age(OR=1.045, 95%CI: 1.023-1.066), Glasgow Coma Scale(GCS)≤8(OR=4.128, 95%CI: 2.161-7.887), hematoma breaking into ventricle(OR=3.071, 95%CI: 1.744-5.408)and hematoma volume >30 mL(OR=5.802, 95%CI: 3.327-10.117). In the training set, the area under the curve(AUC)of the nomogram model was 0.892, which was higher than that of the clinical model(0.814)and the radiomics model(0.862), and the difference was statistically significant(Z=3.356, 2.231, P=0.000 8, 0.025 7). Conclusion The nomogram model can effectively predict the 90-day outcomes for supratentorial sICH patients, which is helpful for clinical decision-making.

Key words: Spontaneous intraparenchymal hematomas, Radiomics, Nomogram, Prognosis

CLC Number: 

  • R574
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