Journal of Shandong University (Health Sciences) ›› 2020, Vol. 58 ›› Issue (10): 25-31.doi: 10.6040/j.issn.1671-7554.0.2020.0712

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A dynamic modeling study on the effects of Wuhan traffic control and centralized quarantine measures on COVID-19 epidemic

JIN Xinye, LU Zhenzhen, DING Zhongxing, CHEN Feng, PENG Zhihang   

  1. School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, China
  • Published:2020-10-08

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Abstract: Objective To quantitatively evaluate the effects of traffic control and centralized quarantine measures on COVID-19 epidemic in Wuhan, so as to provide scientific basis for epidemic prevention and control. Methods The SEIAHR model was established based on SEIR dynamic model, which took into account the characteristics of asymptomatic carriers and unconfirmed quarantined patients. Based on the timing of prevention measures, the epidemic was divided into three stages, the parameters were fitted, the basic reproduction numbers of different stages were calculated, and the development trend of epidemic was predicted. Results The R0 decreased dramatically. The R0 of the three stages were 3.684 1(95%CI: 3.106 1-4.048 0), 2.178 8(95%CI: 1.725 8-3.577 6)and 0.362 5(95%CI: 0.349 9-0.367 6), respectively. Due to the traffic control travel and centralized quarantine, the peak of the disease moved forward from April 19 to March 14, 2020. The scale of the epidemic had also been reduced by prevention and control measures. Conclusion The traffic control and centralized quarantine measures implemented in Wuhan were effective for the epidemic control, which can provide reference for other countries.

Key words: Coronavirus disease 2019, SEIAHR infectious disease dynamics model, Traffic control, Centralized quarantine, Basic reproduction number

CLC Number: 

  • R181.1
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