长脉宽1064nmNd:YAG激光治疗中重度痤疮伴痤疮后红斑的疗效

doi:10.6040/j.issn.1671-7554.0.2015.507

山东大学学报（医学版） ›› 2015, Vol. 53 ›› Issue (11): 85-88.doi: 10.6040/j.issn.1671-7554.0.2015.507

长脉宽1064nmNd:YAG激光治疗中重度痤疮伴痤疮后红斑的疗效

李平平¹, 梁伟², 张真¹, 李莹¹, 高静¹, 马跃¹

1. 山东大学口腔医院特诊科, 山东济南 250012;
2. 山东大学口腔医院综合科, 山东济南 250012

收稿日期:2015-05-22 出版日期:2015-11-10 发布日期:2015-11-10
通讯作者: 马跃.E-mail:mayue@sdu.edu.cn E-mail:mayue@sdu.edu.cn
基金资助:
山东省科技发展计划(2014GSF118124);山东大学口腔医院医疗新技术启动基金项目(20140303)

Efficacy of long-pulsed 1 064 nm Nd:YAG laser in the treatment of moderate to severe acne complicated with post-acne erythema

LI Pingping¹, LIANG Wei², ZHANG Zhen¹, LI Ying¹, GAO Jing¹, MA Yue¹

1. VIP Center, Stomatology Hospital of Shandong University, Jinan 250012, Shandong, China;
2. Department of General Dentistry, Stomatology Hospital of Shandong University, Jinan 250012, Shandong, China

Received:2015-05-22 Online:2015-11-10 Published:2015-11-10

摘要/Abstract

摘要： 目的探讨长脉宽1 064 nm Nd:YAG激光治疗复发性中重度痤疮伴痤疮后红斑的临床疗效和安全性.方法选取20例复发性中重度痤疮伴痤疮后红斑患者,采用长脉宽1 064 nm Nd:YAG激光,光斑直径6.0 mm,能量25～30 J/cm²,频率3.0 Hz,脉宽20~40 ms,治疗病变部位,治疗间隔1周,治疗8次,治疗前后拍照并对皮损进行计数,实验结束后行疗效分析比较.结果 20例患者经过8次治疗,基本痊愈17例,显效3例,总有效率100％,皮损平均计数较治疗前有明显下降,治疗前后差异有统计学意义(P<0.05);同时皮肤质地较治疗前有改善,90%以上患者表示满意.早期炎性皮损的治疗效果优于红斑,二者的疗效差异有统计学意义(P<0.05).术后不良反应为暂时性红斑.结论长脉宽1 064 nm Nd:YAG激光治疗中重度痤疮伴痤疮后红斑疗效确切,安全性高,无明显不良反应,是一种治疗痤疮和持久性痤疮后红斑安全、有效的新方法.

关键词: 痤疮, 痤疮后红斑, Nd:YAG激光, 激光治疗

Abstract: Objective To elucidate the efficacy and safety of long-pulsed 1064nm Nd:YAG laser in the treatment of moderate to severe acne complicated with post-acne erythema. Methods A total of 20 cases of moderate to severe acne complicated with post-acne erythema were recruited, who were treated with long-pulsed 1 064 nm Nd:YAG laser. The laser parameters were: 25~30 J/cm², 3.0 Hz, 20~40 ms pulse duration, 6.0 mm spot size. All patients were treated once a week for 8 weeks. Pictures of acne lesions were taken and the numbers were recorded before and after treatment. Results Of all 20 cases, 17 were cured, and 3 were improved. The total effective rate was 100%. The number of acne lesions was significantly reduced (P<0.05). Meanwhile, the texture of the skin was improved, and more than 90% patients were satisfied. The treatment effect of early inflammatory lesions was better than that of acne erythema (P<0.05). The side effect was transient erythema after treatment. Conclusion s Long-pulsed 1 064 nm Nd:YAG laser is safe and effective in the treatment of moderate to severe acne with acne erythema. It is a new therapeutic approach for acne and persistent post-acne erythema.

Key words: Laser treatment, Acne, Post-acne erythema, Nd:YAG laser

中图分类号:

R782.3

李平平, 梁伟, 张真, 李莹, 高静, 马跃. 长脉宽1064nmNd:YAG激光治疗中重度痤疮伴痤疮后红斑的疗效[J]. 山东大学学报（医学版）, 2015, 53(11): 85-88.

LI Pingping, LIANG Wei, ZHANG Zhen, LI Ying, GAO Jing, MA Yue. Efficacy of long-pulsed 1 064 nm Nd:YAG laser in the treatment of moderate to severe acne complicated with post-acne erythema[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2015, 53(11): 85-88.

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长脉宽1064nmNd:YAG激光治疗中重度痤疮伴痤疮后红斑的疗效

Efficacy of long-pulsed 1 064 nm Nd:YAG laser in the treatment of moderate to severe acne complicated with post-acne erythema

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