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山东大学学报(医学版) ›› 2011, Vol. 49 ›› Issue (6): 155-.

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河南省18岁以下人群甲型H1N1流感抗体水平调查分析

僧明华,蒋红丽,封秀红,郭永豪,张肖肖,郭万申,范军星   

  1. 河南省疾病预防控制中心, 郑州  450016
  • 收稿日期:2010-11-16 出版日期:2011-06-10 发布日期:2011-06-10
  • 通讯作者: 范军星(1972- ),男,硕士研究生,主要从事流行病预防控制工作。 E-mail:fanjx@hncdc.com.cn
  • 作者简介:僧明华(1983- ),女,硕士研究生,主要从事流行病预防控制工作。 E-mail:sengminghua@126.com

Levels of the antibody to swine-origin influenza A(H1N1) virus in the  population under 18 years in Henan Province  

SENG Ming-hua, JIANG Hong-li, FENG Xiu-hong,  GUO Yong-hao,  ZHANG Xiao-xiao, GUO Wan-shen,  FAN Jun-xing   

  1. Center for Disease Control and Prevention of Henan Province, Zhengzhou 450016, China
  • Received:2010-11-16 Online:2011-06-10 Published:2011-06-10

摘要:

目的      了解河南省18岁以下人群甲型H1N1流感抗体水平,为甲流防控提供相关依据。方法      采用微量血凝抑制试验对国家卫生部“甲型H1N1流感血清学横断面调查”的2020人(≤18岁)进行甲型H1N1流感抗体水平检测。结果       河南省18岁以下人群血清抗体阳性率为29.60%,13~18岁、7~12岁、0~6岁阳性率分别为45.70%、25.67%、23.71%,各年龄组阳性率比较差异有统计学意义(χ2=80.07,P<0.01)。城乡有差异(郑州市35.47%、其他市36.00%、农村23.67%)。接种疫苗人群抗体水平(63.89%)显著高于未接种人群(25.91%),χ2=117.18,P<0.01;有无流感样症状者的抗体阳性率差异无统计学意义(χ2=0.75, P>0.01)。结论      18岁以下人群具有一定的甲型H1N1流感抗体,但抗体水平较低,人群普遍易感,建议提高甲型H1N1流感疫苗接种率,进一步加强甲型H1N1流感防控措施。

关键词: 甲型H1N1流感;甲流抗体;阳性率

Abstract:

Objective      To detect levels of the antibody to swine-origin influenza A(H1N1) virus in the population under 18 years in Henan Province, and to provide data for a new preventive policy on swineorigin influenza A(H1N1) virus. Methods      A total of 2020 residents under 18 years, involved in a research program of the Ministry of Health named as  “Cross-sectional study of swine-origin influenza A (H1N1) influenza infection situation”,  were surveyed and a blood test with routine micro-hem agglutination inhibition test was done. Results      The positive rate of the antibody in the population under 18 years was 29.60%, and the rates in the three age groups were 45.70%(1318 years), 25.67%(7-12 years) and 23.71%(0-6 years), respectively. There were statistically significant differences among the three groups(χ2=80.07, P<0.01). Positive rates of the antibody in the three areas showed differences(35.47% in the provincial capital, 36.00% in other cities and 23.67% in the rural area). The positive rate of the antibody in the vaccinated population (63.89%) was significantly higher than in the unvaccinated population(25.91%)(χ2=117.18, P<0.01). There was no significant difference between people with symptoms of influenzalike illness(ILI) and people without(χ2=0.75, P>0.01). Conclusion       Levels of the antibody to swine-origin influenza A (H1N1) virus are low in the population under 18 years in Henan Province. Strengthening vaccination and improving treatment of children are recommended strategies for swine-origin influenza A (H1N1) virus control and prevention.

Key words: Swine-origin influenza A(H1N1)  virus; Antibody to swine-origin influenza A (H1N1) virus; Positive rate

中图分类号: 

  • R511.7
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