山东大学学报 (医学版) ›› 2020, Vol. 58 ›› Issue (3): 118-124.doi: 10.6040/j.issn.1671-7554.0.2020.052
• • 上一篇
于璐1,王彩娇2,刘超3,孙明霞4,彭化海3, 于文倩1,徐欣1,谈万业3
YU Lu1, WANG Caijiao2, LIU Chao3, SUN Mingxia4, PENG Huahai3, YU Wenqian1, XU Xin1, TAN Wanye3
摘要: 目的 对牙源性腺样瘤患者的临床资料进行回顾性分析,对其诊断及治疗方法进行归纳和总结。 方法 收集山东大学齐鲁医院口腔颌面外科2011年7月至2019年7月间牙源性腺样瘤的患者,整理牙源性腺样瘤的临床表现、诊断及治疗方法,对患者预后情况进行随访,归纳肿瘤的发生规律与治疗方法。按肿瘤发生的位置,将患者分为上颌组与下颌组,利用Fisher确切概率法,检验患者性别、年龄以及原发肿瘤大小与肿瘤发生位置之间的关系。 结果 共收集牙源性腺样瘤病例15例。其中7例男性患者,8例女性患者;发生在上颌者9例,发生在下颌者6例。Fisher确切概率法检验,15例患者中,直径>3 cm的牙源性腺样瘤多发于下颌骨。患者治疗均采用肿瘤刮除术,治疗效果良好。患者随访5个月~8年,预后均良好,无复发,无严重并发症。 结论 牙源性腺样瘤临床少见,较难得出具体诊断,需要病理检查方能明确诊断。对牙源性腺样瘤而言,刮除术治疗效果可靠,患者预后良好。
中图分类号:
[1] | La Monaca G, Pranno N, di Gioia CRT, et al. Surgical management of extrafollicular variant of adenomatoid odontogenic tumor in the maxillary posterior region [J]. Case Rep Dent, 2019. doi: 10.1155/2019/3787696. |
[2] | Adel KE. WHO classification of head and neck tumors [M]. 4th edition. Lyon: International Agency for Research on Cancer, 2017: 221-222. |
[3] | Prasad G, Nair P, Thomas S, et al. Extrafollicular adenomatoid odontogenic tumour [J]. BMJ Case Rep, 2011, 2011. doi:10.1136/bcr.03.2011.3963. |
[4] | 李铁军. 牙源性肿瘤的WHO(2005)新分类 [J]. 现代口腔医学杂志, 2007, 21(4): 337-339. |
[5] | Wright JM, Vered M. Update from the 4th edition of the World Health Organization classification of head and neck tumours: odontogenic and maxillofacial bone tumors [J]. Head Neck Pathol, 2017, 11(1): 68-77. |
[6] | Philipsen HP, Reichart PA, Siar CH, et al. An updated clinical and epidemiological profile of the adenomatoid odontogenic tumour: a collaborative retrospective study [J]. Oral Pathol Med, 2007, 36(7): 383-393. |
[7] | Rick GM. Adenomatoid odontogenic tumor [J]. Oral Maxillofac Surg Clin North Am, 2004, 16(3): 333-354. |
[8] | 王应霞, 潘国庆, 雷梓, 等. 牙源性腺样瘤9例临床病理分析 [J]. 临床与实验病理学杂志, 2019, 35(6): 702-704. WANG Yingxia, PAN Guoqing, LEI Zi, et al. Clinical and pathological analysis of 9 cases of adenomatoid odontogenic tumors [J]. Chinese Journal of Clinical and Experimental Pathology, 2019, 35(6): 702-704. |
[9] | Bilodeau EA, Collins BM. Odontogenic cysts and neoplasms [J]. Surg Pathol Clin, 2017, 10(1): 177-222. |
[10] | Kurra S, Gunupati S, Prasad PR, et al. An adenomatoid odontogenic cyst(AOC)with an assorted histoarchitecture: a unique entity [J]. J Clin Diagn Res, 2013, 7(6): 1232-1235. |
[11] | Reichart PA, Philipsen HP, Khongkhunthian P, et al. Immunoprofile of the adenomatoid odontogenic tumor [J]. Oral Dis, 2017, 23(6): 731-736. |
[12] | Chhavi Jindal, Reena Bhola Sarkar, Jessica Grewal, et al. Mural adenomatoid odontogenic tumour as anterior mandibular swelling: a diagnostic challenge [J]. J Clin Diagn Res, 2014, 8(6): ZD25-ZD27. |
[13] | Sharma N, Passi S, Kumar VV. Adenomatoid odontogenic tumor: as an unusual mandibular manifestation [J]. Contemp Clin Dent, 2012, 3(Suppl 1): S29-32. |
[14] | Bhatt R, Dave J, Nalawade TM, et al. Adenomatoid odontogenic tumour in mandible in a 14-year-old boy [J]. BMJ Case Rep, 2013, 2013.doi: 10.1136/bcr-2013-010287. |
[15] | Narayanan VS, Naidu G, Ragavendra R, et al. Adenomatoid odontogenic tumor of the mandible with unusual radiographic features: a case report [J]. Imaging Sci Dent, 2013, 43(2): 111-115. |
[16] | Rai HK, Pai SM, Dayakar A, et al. Adenoid ameloblastoma with dentinoid. A rare hybrid variant [J]. Oral Maxillofac Pathol, 2017, 21(2): 319. |
[17] | Rezvani. G, Donoghue. M, Reichart. PA, et al. Case presentation of concomitant and contiguous adenomatoid odontogenic tumor andfocal cemento-ossifying dysplasia [J]. Open Dent J, 2015, 9: 340-345. doi:10.2174/1874210601509010340. |
[18] | Dhupar V, Akkara F, Khandelwal P. An unusually large aggressive adenomatoid odontogenic tumor of maxilla involving the third molar: a clinical case report [J]. Eur J Dent, 2016, 10(2): 277-280. |
[19] | Shaikh S, Bansal S, Desai RS, et al. Aggressive adenomatoid odontogenic tumor of the mandible: a rare case report and review of the literature [J]. J Oral Maxillofac Pathol, 2018, 22(Suppl 1): S11-S15. |
[20] | Kalia V, Kalra G, Kaushal N, et al. Maxillary adenomatoid odontogenic tumor associated with a premolar [J]. Ann Maxillofac Surg, 2015, 5(1): 119-122. |
[21] | Virupakshappa D, Rajashekhara BS, Manjunatha BS, et al. Adenomatoid odontogenic tumour in a 20-year-old woman [J]. BMJ Case Rep, 2014, 2014. doi: 10.1136/bcr-2013-010436. |
[22] | Erdur EA, Ileri Z, Ugurluoglu C, et al. Eruption of an impacted canine in an adenomatid odontogenic tumor treated with combined orthodontic and surgical therapy [J]. Am J Orthod Dentofacial Orthop, 2016, 149(6): 923-927. |
[23] | Nomura M, Tanimoto K, Takata T, et al. Mandibular adenomatoid odontogenic tumor with unusual clinicopathologic features [J]. J Oral Maxillofac Surg, 1992, 50(3): 282-285. |
[24] | Takigami M, Uede T, Imaizumi T, et al. A case of adenomatoid odontogenic tumor with intracranial extension [J]. No Shinkei Geka, 1988, 16(6): 775-779. |
[25] | Zhou CX, Gao Y. Adenomatoid odontogenic tumor: a report of a rare case with recurrence [J]. J Oral Pathol Med, 2007, 36(7): 440-443. |
[1] | 王婧,刘小转,许芳芳. 肝豆状核变性的ATP7B基因变异分析及产前诊断[J]. 山东大学学报 (医学版), 2022, 60(2): 32-36. |
[2] | 初竹秀,赵文静,李小燕,孔晓丽,马婷婷,江立玉,杨其峰. 218例女性乳腺癌患者行新辅助化疗及伴随分子标志物改变的临床价值[J]. 山东大学学报 (医学版), 2021, 59(9): 130-139. |
[3] | 鞠建华,杨镇业,李青连,韩亚楠,李艳青,乔伊君,杨虎,张华然. 微生物药物研究开发现状与思考[J]. 山东大学学报 (医学版), 2021, 59(9): 43-50,63. |
[4] | 田瑶天,王宝,李叶琴,王滕,田力文,韩波,王翠艳. 基于可解释性心脏磁共振参数的机器学习模型预测儿童心肌炎的预后[J]. 山东大学学报 (医学版), 2021, 59(7): 43-49. |
[5] | 夏晓娜,黄召弟,任庆国,刘枫,邓贺,任国荣,段建东,王韶玉. CT双期增强扫描对182枚甲状腺良恶性结节的诊断价值[J]. 山东大学学报 (医学版), 2021, 59(7): 57-62. |
[6] | 王宁,郭振江,张媛媛,王晶,郭伟,王金荣,崔朝勃. 定期超声检查在中心静脉置入设备相关深静脉血栓诊治中的应用价值[J]. 山东大学学报 (医学版), 2021, 59(7): 63-67. |
[7] | 杜娇娇,庄向华,陈诗鸿,王雪萌,姜冬青,吴菲,韩晓琳,华梦羽,宋玉文. 绝经后骨质疏松症患者血清IL-31、IL-33表达变化[J]. 山东大学学报 (医学版), 2021, 59(6): 45-50. |
[8] | 陈诗鸿. 糖皮质激素性骨质疏松症研究进展[J]. 山东大学学报 (医学版), 2021, 59(6): 33-37. |
[9] | 司海朋,张文灿,李乐,周鑫. Kümmell's病的危险因素和诊治研究进展[J]. 山东大学学报 (医学版), 2021, 59(6): 25-32. |
[10] | 李敏启,杜娟,杨盼盼,寇雨莹,柳珊珊. 氧化应激调控骨质疏松症的研究进展[J]. 山东大学学报 (医学版), 2021, 59(6): 16-24. |
[11] | 程晓光,卢艳慧. 男性骨质疏松:一个长期被忽视的问题[J]. 山东大学学报 (医学版), 2021, 59(6): 5-9. |
[12] | 江勇,宋剑刚,朱大侠,刘礼剑. 柚皮素通过调控巨噬细胞NLRP3炎症小体活化对脓毒症致急性肺损伤的影响[J]. 山东大学学报 (医学版), 2021, 59(1): 14-21. |
[13] | 贾明旺,廖广园,熊明媚,徐文婷,王银玲,王懿春. 84例妊娠合并肺高血压患者预后的临床分析[J]. 山东大学学报 (医学版), 2021, 59(1): 34-39. |
[14] | 甄秋来,吕欣然,叶辉,丁绪超,柴小雪,胡辛,周明,曹莉莉. 基于TCGA数据库预测结肠癌预后基因及其临床应用价值[J]. 山东大学学报 (医学版), 2021, 59(1): 64-71. |
[15] | 尹义龙,袭肖明. 眼科疾病智能诊断方法最新进展[J]. 山东大学学报 (医学版), 2020, 58(11): 33-38. |
|